Springboard Health Nutrition notebook Health information
 
Other Nutrients 296 pixels Return home
2 pixels

FIBER - A Simple Overview

MISCONCEPTIONS ABOUT FIBER:

  • Bran is synonymous with fiber
  • All fiber is fibrous or stringy
  • All fiber tastes the same

WHAT FIBER IS:

  • Fiber is the indigestible remnants of plant cells
  • Fiber plant remnants come in 5 main types from many food sources
  • There are many differences in physiological impact among these five types

THE 5 MAIN TYPES OF FIBER ARE:

  • Cellulose
  • Hemicellulose
  • Pectin
  • Lignins
  • Gums and Mucilages

WHAT FIBER DOES

CELLULOSE

SOURCES: Fruits, vegetables, bran, whole meal, bread, and beans.

IT DOES:

  • Increase bulk of intestinal waste and eases it quickly through the colon.
  • Prevent constipation and helps diarrhea
  • By the above actions dilutes and flushes cancer causing toxins out of the
  • intestinal tract.
  • Help level out glucose in the blood.
  • Help curb weight gain due to its ability to fill you up without fattening you out.

HEMICELLULOSE

IT DOES:

  • Help relieve constipation.
  • Water down carcinogens in the bowel.
  • Aid in weight reduction.

PECTIN

SOURCES:

Apples, citrus fruits, grapes, berries, and bran.

IT DOES:

  • Lower cholesterol significantly.
  • Aid in the elimination of bile acids through the intestinal tract,
  • short circuiting the development of gall stones and colon cancer.

IT DOES NOT:

  • Deter constipation.

GUMS AND MUCILAGES

SOURCES: Locust bean gum, karaya gum, guar gum, oat bran, etc.

IT DOES:

  • Lower cholesterol significantly.
  • Help diabetics handle blood sugar better.

LIGNINS

SOURCES:

Cereals, bran, whole meal flour, raspberries, strawberries, brussel sprouts, cabbage, spinach, kale, parsley, and tomatoes.

IT DOES:

  • Flush bile acids and cholesterol out of the intestines.
  • Aid in the prevention of gall stones.

FIBER – A More Detailed Explanation

DESCRIPTION

Dietary fibers are vegetable substances not digestible by the enzymes of the alimentary tract. They are derived from plant cell walls and from the nonstructural polysaccharides in natural foods. Fibers include cellulosics and hemicellulosics, gums, pectins, and lignins.

FOLKLORE

Brans and pectins obtained from dietary sources are probably the most effective types of fiber. Experimental trials indicate that fiber protects the blood and tissue against various dietary and environmental toxins and carcinogens by maintaining the good health of the bowel, and rendering toxins inert by complexing with them.

Low fiber intake is conclusively related to obesity, diabetes mellitus, coronary heart disease, diseases of the colon - including cancer - and to various other modern ailments. Fiber-rich diets lead to decreases in body weight, blood sugar levels, serum cholesterol levels, and levels of total triglycerides, with corresponding improvements in health. Low concentrations of serum lipids and low incidence of coronary heart disease are found in Seventh Day Adventists, Trappist monks, strict vegetarians, lacto-vegetarians, and those using the Zen macrobiotic diet.

METHOD OF ACTION

Dietary Fiber Reduces Serum Cholesterol Levels

Not all dietary fibers produce the same metabolic effects. It is helpful, therefore, to subdivide fibers into groups according to their mode of action.

Cellulosics and Hemicellulosics include those non-digestible portions of many plants, including bran, cereals, grains, beans, peppers, carrots and cabbage, that absorb water, and increase in bulk. They have a normalizing effect on the bowel, prevent constipation by accelerating the passage of material through the large intestine, and protect the body from several diseases, including cancer, colitis, and spastic colon.

Gums include the extremely water loving material found in oats, guar, Irish moss and locust beans, to name a few. Gums are also inert, simply absorbing water, swelling, and serving much the same purpose as the cellulosics.

Pectins are the water soluble substances that bond adjacent cell walls in the tissues of many plants, including apples, citrus fruits, potatoes, strawberries and green beans. They yield a gel which is the basis of fruit jellies. Pectins and gums bind with bile acids, and decrease cholesterol levels and fat absorption.

Lignins are plant polymers that combine with cellulose to form plant cell walls and the cementing material between them. Lignin has been found to reduce time of passage of stomach contents, bind with bile acids and lower cholesterol levels. Pectin has the greatest effect on cholesterol levels. In 1957, it was found that dietary pectin (in rats) increased the excretion of lipids, cholesterol and bile acids. Thereafter, an increasing number of reports verified those data and extended them to include humans. By 1977, the effect had been thoroughly documented and established. For example, in one three week study in humans, plasma cholesterol fell about 13% or more as long as apple pectin was administered (about 15 gm/day). When the pectin was withdrawn, cholesterol levels rose.

It is believed that pectins operate by binding with bile acids, thereby decreasing cholesterol and fat absorption. The results of most experiments indicate that mucilaginous fibers such as pectin, plantain and fenugreek are much better in decreasing serum cholesterol levels than are particulate fibers such as are found in wheat bran. It is important to note that pectin reduces lymphatic cholesterol absorption best when the diet contains cholesterol. (Pectin is also effective when used for producing regressions in, and preventing the formation of gallstones.) A few studies show that bran from wheat, corn and sugar beets lowers serum cholesterol levels, but most data fail to show a significant effect in that direction. The presence of other dietary factors may finally determine to what extent bran is effective. Oat bran, which is partly mucilaginous, does lower cholesterol levels substantially.

Cellulose does not lower cholesterol levels except when administered in large quantities, and lignins have variable effects. In summary, it appears that mucilaginous fiber (pectin, oat bran) rather than particulate fiber (cellulosics, most brans, lignins) is responsible for decrease serum cholesterol levels. Several mechanisms have been postulated to explain the effects of fiber. It may alter gastric emptying time and intestinal transit rates, thereby decreasing the availability of carbohydrates to be absorbed. Or, since dietary fibers swell (each part of polysaccharide may hold 100 parts water), they may simply be filling, limiting the amount of food that can be eaten. In this manner the fiber actually displaces foods that contribute saturated fat and cholesterol to the diet. By modulating glucose absorption, dietary fiber could prevent or reduce obesity.

The most likely explanation is that the mucilaginous fibers form gels in the small intestine that interfere with the absorption of both cholesterol and bile acids. This hypothesis is supported directly by the finding that pectin reduces lymphatic cholesterol absorption best when the diet contains cholesterol Pectin also increase the excretion of neutral bile acids because its ionic charge imparts a high affinity for solubilized biliary salts. Pectin-salt complexes are excreted as waste, resulting in a reduction of the available biliary salts which would normally be used by the body to make possible the absorption of cholesterol. This, in turn, may indirectly lower cholesterol levels even further because the body will now use up even more endogenous (non-dietary) cholesterol to produce more biliary acids.

Bran, though it doesn’t lower cholesterol levels as surely as pectin does, has nevertheless been shown to help prevent the precipitation of cholesterol from the bile that produces gallstones. Bile is a finely balanced solution of cholesterol, bile salts and phospholipids. The oversecretion of cholesterol or the undersecretion of bile salts leads to supersaturation of cholesterol that then precipitates as gallstones. Bran increases the size of the bile salt pools when necessary and otherwise normalizes the balance between the major components of the bile. Thirty grams of bran per day has been shown to significantly improve the bile composition in several patients with cholesterol gallstones.

Pectin and Other Dietary Fiber Protects the Body from Toxins

Russian research has shown that heavy metals, such as lead and mercury, are excreted harmlessly and much more efficiently when pectin is included in the diet. Apple pectin, rice bran, wheat bran, alfalfa fiber and burdock root fiber, along with other sources of dietary fiber, have been shown to protect the body, and especially the gut, against the toxic effects of several common food additives, including amaranth (FD & C No. 2), Tween 60 (polyoxyetheylen sorbitan monostearate), sodium cyclamate, tartrazine (FD 7 C Yellow No. 5), and Sunset Yellow (FD &C Yellow No. 6). Possible modes of action include a binding of the additives with the fiber, thereby preventing absorption, or perhaps the fiber prevents adverse effects through an action on the digestive process or gut bacteria.

Pectin May Be Used In The Management of Diabetes

There is growing evidence that the regular use of pectin may lessen the severity of diabetes, presumably because pectin absorbs sugars and carbohydrates, releasing them slowly in the intestinal tract. This slow release produces a much slower and steady rise in blood sugar levels. It has been suggested that fiber-depleted diets actually may precipitate diabetes mellitus. One study showed that adding pectin (and guar) to meals significantly reduced glucose and insulin levels in nondiabetic as well as non-insulin-requiring diabetic patients following meals. Insulin-requiring patients experienced a lowering of glucose levels. In a similar study, insulin-requiring diabetic patients experience a continuing effect of lowered plasma glucose when placed on a long term pectin-rich diet. These patients eventually required much less insulin.

DRUG INTERACTIONS

Known Interactions

It is known that the use of dietary fiber, especially pectin, can eventually produce long lasting reduction of blood glucose levels. This in turn would potentiate the effects of insulin injections.

Possible Interactions

None

Comments

The use of large amounts of fiber on a continuous basis may partially block the digestion, absorption or reabsorption of a wide variety of drugs and fat soluble vitamins.

The antidiabetic ability of fiber may be decreased by concomitant use of acetazolamide, oral contraceptives, corticosteroids, dextrothyroxin, epinephrine, ethanol, glucagon, and marijuana.

The antidiabetic effects of fiber may be decrease when used in conjunction with phenothiazines, rifampin, thiazide diuretics, and thyroid hormones.

The antidiabetic action of fiber may be enhanced when it is used with allopurinal, anabolic steroids, chloramphenicol, chlofibrate, fenfluramine, guanethidine, MAO inhibitor, phenylbutazone, probenecid and phenyramidol.

The antidiabetic action of the herb may be enhanced when used in conjunction with salicylates, sulfinpyrazone, sulfonamides, and tetracyclines.

REFERENCES

Mowrey, D.B., Ph.D., Experimental Psychology, Brigham Young U. Director of Nebo Institute of Herbal Sciences. Director of Behavior Change Agent Training Institute. Director of Research, Nova Corp.

American Hospital Formulary Service. American Society of Hospital Pharmacists . Washington, D.C.

Goodman, L.S. & A. Gilman. 1975. The Pharmacological Basis of Therapeutics. MacMillan, New York.

Hansten, P.D. 1979. Drug Interactions, 4th ed. Lea & Febiger, Philadelphia.

List, P.H. & L. Hoerhammer. 1969-1976. Hagers Hanbuch der Pharmazeutischen Praxis, vols. 2-5. Springer-Verlag, Berlin.

Bressler, R., M.D. Bogdonoff & G.J. Subak-Sharpe. 1981. The Physicians Drug Manual. Doubleday & Company, Inc. Garden City, New York. 1213 pp.

Kastrup, I.E., ed. 1981. Drug Facts and Comparisons, 1982 ed. Facts and Comparisons Division, J. P. Lippincott Co., Philadelphia (St. Louis).

Marx, A.V. &Adler, E. “Ueber die blutzucherherbasetzende wirkung von herba, urticae dioicae.” Naunyn-Chmied. Arch. Parmakol., pp. 112, 29-30, 56, 1926.

Trowell, H., “The Development of the Concept of Dietary Fiber in Human Nutrition.” Amer. Journal of Clin. Nut. 31 (10), pp. 3-11, 1978.

Southgate, D.A.T., “Dietary Fiber: Analysis and Food Sources,” Amer. Journal of Clin. Nut., 31, p.107 1978.

Levin, B., Horwitz, D., “Dietary Fiber,” Medical Clinics of North America, 62(5): 1043-1055, 1979.

Albrink, M.J., “Dietary Fiber, Plasma Insulin and Obesity,” Amer. Journal of Clin. Nut., 31(10): pp. 277-278, 1978.

Reiser, S., “Effects of Dietary Fiber on Parameters of Glucose Tolerance in Humans,” in Inglett, G.D. & Falkehag, S.I., eds. Dietary Fibers. Chemistry and Nutrition, Academic Press, New York, 1979, p. 173.

Phillips, R.L., Lemon, F.R., Beeson, W.L., et.al., “Coronary Heart Disease Mortality Among Seventh-Day Adventists with Differing Dietary Habits: a Preliminary Report,” Amer. Journal of Clin. Nut., 31 (Suppl), p. 191, 1978.

Barrow, J.G., Quinlan, C.B., Edmando, R.E., et. al., “Prevalence of Atherosclerotic Complications in Trappist and Benedictine Monks (abstract),” Circulation, 24, pp. 881-82, 1961.

Hardinger, M.G., Chambers, A.C., Crooks, H., et. al., “Nutritional Studies of Vegetarians, 111. Dietary Levels of Fiber,” Amer. Journal of Clin. Nut., 6(5), pp. 523-25, 1958.

Sacks, F.M., Castelli, W.P., Donner, A., et. al., “Plasma Lipids and Lipoproteins in Vegetarians and Controls,” New England Journal of Medicine, 292(22: pp. 1148-51, 1975.

Van Berge-Henegoumen, G.P., Huybregts. W. Van De Werf, S., Demacker, P. & Schade, R.W., “Effect of a Standardized Wheat Bran Preparation on Serum Lipids in Young Healthy Males,” Amer. Journal of Clin. Nut., 32, pp. 794-98, 1979.

Heaton, K.W., Pomare, E.W., “Effects of Bran on Blood Lipids and Calcium,” Lancet, 1, pp. 49-50, 1974.

Anderson, J.W. et. al., “Plant Fiber, Carbohydrate and Lipid Metabolism,” Amer. Journal of Clin. Nut., 32(2), pp. 346-363, 1979.

Lindner, P. & Moeller, B., “Lignin: A Cholesterol-Lowering Agent?,” Lancet, 2, p. 1259, 1973.

Kay, R.M., &Truswell, A.S., “Effect of Citrus Pectin on Blood Lipids and Fecal Steroid Excretion in Man,” Amer. Journal of Clin. Nut., 30(2), pp. 171-175, 1977.

Story, J.A., Kritchevsky, D. & Eastwood, M.A., Dietary Fibers, Chemistry and Nutrition, Academic Press, 1979, p. 49.

Pomare, E.W., & Heaton, K.W., “Alteration of Bile Salt Metabolism by Dietary Fiber (bran),” British Medical Journal, 4, pp. 262-264, 1973.

Watts, J.M., Jablowski, P. &Toouli, J., “The Effect of Added Bran to the Diet on the Saturation of Bile in People Without Gallstones,” Amer. Journal of Surgery, 135(3), pp. 321-324, 1978.

McDougall, R., Ykymyshyn, D., Walker, K., et. al., “Effect of Wheat Bran on Serum Lipoproteins and Biliary Lipids,” Canadian Journal of Surgery, 212(5), pp. 433-435, 1978.

Pomare, E.W., Heaton, W.W., Low-Beer, T.S. & Espiner, H.J., “The Effect of Wheat Bran Upon Bile Salt Metabolism and Upon the Lipid Composition of Bile in Gallstone Patients,” Amer. Journal of Digestive Diseases, 21(7), pp. 521-526, 1976.

Heaton, K. in Refined Carbohydrate Foods and Disease. Burkitt, D.P. &Trowell, H.C., eds. Academic Press, London, 1975, p. 173.

Apostolou, I, Goranov, Il, Balabanski, L., Krasteva, A. & Popova, D., “Studies on Serum Lipids in Patients with Hyperlipoproteinemia on Pectin Preparations Diet-Treatment,” Vutreshni Bolesti, 21(5), pp. 51-54, 1982.

Lifshitz, O.D., “Prophylactic Role of Pectin-Containing Foods During Lead Poisonings,” Voprosy Pitaniya, 28(4), pp. 76-77, 1969; and Arkhipova, O.G. & Zorina, L.A. Professional Ne Zabloveaniya V Khimicheskoi Promyshlenmosti, pp. 210-213, 1965.

Ershoff, B.H. & Marshall, W.E., “Protective Effects of Dietary Fiber in Rats Fed Toxic Doses of Sodium Cyclamate and Polyoxyethelene Sorbigan Monostearate (Tween 60),” Journal of Good Science, 40, p. 357, 1975.

Ershoff, B.H. & Thurston, E.W., “Effects of Diet on Amaranth (FD 7 C Red No. 2) Toxicity in the Rat.” Journal of Nutrition, 104, p. 937, 1974.

Ershoff, B.H. “Synergistic Toxicity of Food Additives in Rats Fed A Diet Low in Dietary Fiber,” Journal of Food Science, 41, p. 949, 1976.

Ershoff, B.H., “Effects of Diet on Growth and Survival of Rats Fed Toxic Levels of Tartrazine and Sunset Yellow FCF,” Journal of Nutrition, 107, p, 822, 1977.

Sharma, R.V., Sharma, R.C. & Prasad, Y., “Effect of Pectin on Carbohydrate and Fat Metabolism,” Indian Journal of Medical Research, 76, pp. 771-775, 1982.

Jenkins, D.J.A., Leeds, A.R., Goff, D.V. et. al., “Unabsorbable Carbohydrates and Diabetes Increased Postprandial Hyperglycaemia,” Lancet, 11, p. 172, 1976.

Sharma, R.V., “Effect of Dietary Fiber on Postprandial Hyperglycaemia, Lipid Metabolism (serum cholesterol and serum triglycerides),” M.D. Thesis (Physiology), Agra University, Agra, India, 1978.

Jenkins, D.J.A., Leeds, A.R., Gassullk, M.A.A., Cochet, G., Liberti, K.B.M.M.,“Decrease in Postprandial Insulin and Glucose Concentrations by Guar and Pectin,” Annals of Internal Medicine, 86, pp. 20-23, 1977.

Miranda, P.M.. & Horwitz, D.L., “High Fiber Diets in the Treatment of Diabetes Mellitus,” Annals of Internal Medicine, 88, pp. 482-86, 1978.

Kurz, M. 1968. “Diamox und manifestierung von diabetes millitus,” Wein Medizinische Wochenscrift.

Reddy, C.C. and E.J. Massaro, “Biochemistry of Selenium: A Brief Overview,” Fundamental Applied Toxicology, 3 (1983).

Beaudry, C. & L. Laplante, 1973, “Treatment of Renal Failure from Diabetic Nephropathy with Dadaveric Homograft,” Canadian Medical Association Journal, 100.

Coulson, A. and G. Reaven, “Effect of Source of Dietary Carbohydrate on Plasma Glucose,” Amer. Journal of Clin. Nut. 33, 1980.

Middleton, E. & S.R. Finke, 1968. “Metabolic Response to Epinephrine in Bronchial Asthma,” Journal of Allergy, 42.

Arky, R.A., et. al., 1968. “Irreversible Hypoglycemia, a Complication of Alcohol and Insulin,” Journal of the American Medical Association, 206.

Nord, H.J., et. al., 1970. “Treatment of Congestive Heart Failure with Glucagon,” Annals of Internal Medicine, 72.

Lockhart, R.D., G.F. Hamilton, et. al., 1974. “Anatomy of a Human Body,” Faber and Faber Limited, London, 697 pp.

Arneson, G., 1964. “Phenothiazine Derivatives and Glucose Metabolism,” Journal of Neuropsychiatry, 5, p. 181.

Zilly, W., et. al., 1976. “Induction of Drug Metabolism in Man After Rifampicin Treatment Measured By Increased Hexobarbital and Tolbutamide Clearance,” European Journal of Clinical Pharmacology, 9.

Malins, J.M., 1968. “Diuretics in Diabetes Mellitus,” Practitioner, 201.

Refetoff, S., 1975. “Thyroid Hormone Therapy,” Medical Clinics of North America, 59.

Petersdorf, R.G. and R.D. Adams, 1983. “Harrison’s Principles of Internal Medicine,” 10th ed., McGraw-Hill, New York, 2212 pp.

Lankisch, P.G. and W., Creutzfeldt, “Therapy of Exocrine and Endocrine Pancreatic Insufficiency,” Clin. Gastroenterology, 13, 1984.

Osol, Arthur, 1980, Remington’s Pharmaceutical Sciences, Mack Pub. Co., Penn, 1928 pp.

Turner, R.B., “Estrogen-Like Substance in the Yeast Sacchro-Mycetes Cervaisae,” Science, 220, 1984.

Peaston, M.J.T., & P. Finnegan, 1968. “ A Case of Combined Poisoning with Chlorpropamide, Acetylsalicylic Acid and Paracetamol,” British Journal of Clinical Practice, 22.

Kaegi, A., et. al., 1974. “Arteriovenous-shunt thrombosis. Prevention by Sulfinpyrazone,” New England Journal of Medicine.

Bergman, H., 1965. “Hypoglycemic Coma During Sulfonylurea Therapy,” Acto Med Scand, 177.

472 pixels

Return to top

2 pixels
2 pixels

Copyright © 2004 Springboard All rights reserved.
2 pixels
Left tab 436 Pixels Right tab